Good calculator skills save time and points on the AP Biology exam. These AP Biology calculator tips show exactly how to run a chi-square test, make clear FRQ graphs, and avoid common slip-ups—so you spend time on reasoning, not arithmetic.
Allowed calculators (quick reminder)
- Four-function, scientific (e.g., Casio fx-series), and graphing (e.g., TI-84) are permitted.
- College Board note: bring permitted models, fresh batteries, and follow calculator-use rules on exam day.
Chi-square test — step-by-step (worked example)
Scenario: You expect a 3:1 ratio (75:25) from 100 offspring. Observed: 90 tall, 10 dwarf. Is this difference significant?
- Compute expected counts
- Expected: 75 tall, 25 dwarf.
- Enter data (TI-84)
- Press
STAT→ EDIT. - Put observed counts in L1:
90,10. Put expected counts in L2:75,25.
- Press
- Run Chi-square test (TI-84)
- Press
STAT→ right toTESTS→ select χ²-Test. - For Observed:
L1; Expected:L2; chooseCalculate→ ENTER. - Calculator returns χ² = 12.0, p ≈ 0.0005 (example output).
- Press
- If your calculator doesn’t do χ² tests (generic Casio scientific)
- Compute each term
(O − E)² / Emanually:- Tall: (90−75)²/75 = 225/75 = 3.0
- Dwarf: (10−25)²/25 = 225/25 = 9.0
- χ² = 3.0 + 9.0 = 12.0
- For p-value, either use a graphing calculator/stat app or compare χ² to a chi-square table (df = categories−1 = 1). For χ² = 12, p < 0.01.
- Compute each term
- Interpretation (AP FRQ language)
- Conclusion: “Using a chi-square test (χ² = 12.0, df = 1, p < 0.01), we reject the null hypothesis; the observed counts differ significantly from the expected 3:1 ratio.”
- Note: In FRQs, use χ² value, degrees of freedom, p-value (or significance statement).
Graphing for FRQs — make it exam-ready
Example dataset: enzyme activity at temps (°C):x (°C) = [10, 20, 30, 40]y (rate) = [2.1, 3.8, 5.9, 4.4]
TI-84 keystrokes & steps
- Enter data:
STAT→ EDIT → putxin L1,yin L2. - Turn on scatter:
2ndY=(STAT PLOT) → select Plot1 ON → choose scatter,Xlist = L1,Ylist = L2. - View:
ZOOM→9: ZoomStatto auto-scale to your data. - Best-fit line:
STAT→ right toCALC→4:LinReg(ax+b)(orLinReg), then pressVARS→Y-VARS→Function→Y1to store the regression on the graph →ENTER. - Sketch for FRQ: If teacher expects a trendline, draw the regression line and label slope and intercept (from calculator); if the prompt asks to “connect points,” draw dots and connect in order.
Axis & formatting tips
- Label axes with units (e.g., “Temperature (°C)”, “Rate (µmol/min)”).
- Choose even spacing — tick marks at round numbers. For the example: x from 5–45 with ticks every 10; y from 0–7 with ticks every 1.
- Title optional; clear axis labels required.
Calculator settings & quick checks (do these before the exam)
- Clear statistical lists:
STAT→ EDIT → highlight list name →CLEAR→ENTER. - Reset memory (optional): back up any programs, then reset.
- Mode check: confirm Degree vs Radian (Mode → Degree).
- Turn off plots if you don’t need them (
2nd Y=→ Plot1 OFF). - Battery check: replace batteries day before.
Common mistakes to avoid
- Not clearing old lists (results use old data).
- Wrong parentheses when calculating
(O−E)²/E. - Misreading p-value (e.g., thinking 0.06 < 0.05).
- Wrong degrees of freedom (df = k − 1 for k categories).
- Poor axis scaling (compresses data or misleads slope).
- Forgetting to label axes/units or to state the conclusion in FRQ language.
Practice problems (short)
- Chi-square: Observed 85/15 vs expected 75/25 (total 100). Q: Is difference significant?
Answer/hint: χ² = (10²/75)+(10²/25)=100/75+100/25=1.333+4=5.333; df=1. p ≈ 0.02 → reject. (Use χ²-Test or manual sum.) - Graphing: Plot x = [0,1,2,3], y = [1.2,2.4,3.6,4.8]. Q: What line should you draw?
Answer/hint: Points lie on a line y = 1.2x + 1.2. UseLinRegand store to Y1. - Summary stat: Data = [2,4,6,8]. Q: Mean? Median?
Answer/hint: Mean = 5, median = (4+6)/2 = 5. UseSTAT→CALC→1-Var Stats.
3-question FAQ
Q: Do calculators always give p-values for chi-square?
A: Graphing calculators (TI-84) typically return p; many scientific calculators do not, so use a chi-square table or app if needed.
Q: Should I title my FRQ graphs?
A: Title is optional; always include clear axis labels and units—those are required.
Q: What df do I use for goodness-of-fit?
A: Degrees of freedom = number of categories − 1.
Conclusion
Strong calculator technique converts tedious math into fast, reliable evidence you can use in FRQs. Practice the keystrokes and the checklist until they’re second nature. Download the one-page AP Bio Calculator Cheat Sheet below to print and memorize; you can find it and a helpful score calculator at Here. It’s formatted for quick exam prep.
AP Bio Calculator Cheat Sheet
Quick keystrokes (TI-84)
- Enter lists: STAT → EDIT → put X in L1, Y in L2
- Clear list: highlight list name → CLEAR → ENTER
- Chi-square test: STAT → TESTS → χ²-Test → Observed:L1 Expected:L2 → Calculate
- LinReg (best-fit line): STAT → CALC → LinReg(ax+b) → store to Y1 via VARS → Y-VARS → Function → Y1
- Scatter plot on: 2nd Y= (Stat Plot) → Plot1 ON → choose scatter →
Zoom→9:ZoomStat - 1-Var Stats: STAT → CALC → 1-Var Stats → L1
Manual χ² formula (if no test available)
χ² = Σ((O − E)² / E)
df = k − 1
p from chi-square table or app
Pre-exam checklist (memorize)
- Clear lists and plots
- Confirm Degree/Radian = Degree
- Fresh batteries
- Have formula sheet / table if allowed
- Practice 3 χ² and 3 LinReg problems

























